User profiles for "author:John D Ryan"
John D. RyanUniversity of Oxford Verified email at ndm.ox.ac.uk Cited by 2290 |
[HTML][HTML] Consensus Statement on the definition and classification of metabolic hyperferritinaemia
L Valenti, E Corradini, LA Adams, E Aigner… - Nature Reviews …, 2023 - nature.com
Hyperferritinaemia is a common laboratory finding that is often associated with metabolic
dysfunction and fatty liver. Metabolic hyperferritinaemia reflects alterations in iron …
dysfunction and fatty liver. Metabolic hyperferritinaemia reflects alterations in iron …
[HTML][HTML] Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection
Chronic hepatitis B virus (HBV) infection is a major cause of liver morbidity and mortality
worldwide. While a proportion of the 250 million individuals chronically infected with HBV …
worldwide. While a proportion of the 250 million individuals chronically infected with HBV …
[HTML][HTML] Non-invasive markers of liver fibrosis: adjuncts or alternatives to liver biopsy?
JL Chin, M Pavlides, A Moolla, JD Ryan - Frontiers in pharmacology, 2016 - frontiersin.org
Liver fibrosis reflects sustained liver injury often from multiple, simultaneous factors. Whilst
the presence of mild fibrosis on biopsy can be a reassuring finding, the identification of …
the presence of mild fibrosis on biopsy can be a reassuring finding, the identification of …
[HTML][HTML] An international multidisciplinary consensus statement on MAFLD and the risk of CVD
XD Zhou, G Targher, CD Byrne, V Somers… - Hepatology …, 2023 - Springer
Background Fatty liver disease in the absence of excessive alcohol consumption is an
increasingly common condition with a global prevalence of~ 25–30% and is also associated …
increasingly common condition with a global prevalence of~ 25–30% and is also associated …
Expenditure freeze: the metabolic response of small mammals to cold environments
There is renewed focus on the ecological determinants of animal metabolism and recent
comparative analyses support the physiological expectation that the field metabolic rate …
comparative analyses support the physiological expectation that the field metabolic rate …
Hepatic iron is the major determinant of serum ferritin in NAFLD patients
JD Ryan, AE Armitage, JF Cobbold… - Liver …, 2018 - Wiley Online Library
Abstract Background and Aims Elevated serum ferritin is common in NAFLD, and is
associated with more advanced disease and increased mortality. Hyperferritinaemia in …
associated with more advanced disease and increased mortality. Hyperferritinaemia in …
[HTML][HTML] PYY plays a key role in the resolution of diabetes following bariatric surgery in humans
C Guida, SD Stephen, M Watson, N Dempster… - …, 2019 - thelancet.com
Background Bariatric surgery leads to early and long-lasting remission of type 2 diabetes
(T2D). However, the mechanisms behind this phenomenon remain unclear. Among several …
(T2D). However, the mechanisms behind this phenomenon remain unclear. Among several …
Suppression of a deletion mutation in the gene encoding essential PBP2b reveals a new lytic transglycosylase involved in peripheral peptidoglycan synthesis in S …
In ellipsoid‐shaped ovococcus bacteria, such as the pathogen Streptococcus pneumoniae
(pneumococcus), side‐wall (peripheral) peptidoglycan (PG) synthesis emanates from …
(pneumococcus), side‐wall (peripheral) peptidoglycan (PG) synthesis emanates from …
A multidisciplinary approach to the management of NAFLD is associated with improvement in markers of liver and cardio-metabolic health
A Moolla, K Motohashi, T Marjot, A Shard… - Frontline …, 2019 - fg.bmj.com
Non-alcoholic fatty liver disease (NAFLD) is a globally prevalent health problem, associated
in its more severe forms with increased liver-related and cardiovascular-related morbidity …
in its more severe forms with increased liver-related and cardiovascular-related morbidity …
[PDF][PDF] Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis
Hereditary hemochromatosis (HH) is a common inherited iron overload disorder. The vast
majority of patients carry the missense Cys282Tyr mutation of the HFE gene. Hepcidin, the …
majority of patients carry the missense Cys282Tyr mutation of the HFE gene. Hepcidin, the …