Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis

D Yadav, RH Hawes, RE Brand… - Archives of internal …, 2009 - jamanetwork.com
Background Recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) are
associated with alcohol consumption and cigarette smoking. The etiology of RAP and CP is …

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

DC Whitcomb, J LaRusch, AM Krasinskas, L Klei… - Nature …, 2012 - nature.com
Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long
thought to be the primary causative agent, but genetic contributions have been of interest …

Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitis

GA Coté, D Yadav, A Slivka, RH Hawes… - Clinical …, 2011 - Elsevier
BACKGROUND & AIMS:: Alcohol has been implicated in the development of chronic
pancreatitis (CP) in 60%–90% patients, although percentages in the United States are not …

Multicenter approach to recurrent acute and chronic pancreatitis in the United States: the North American Pancreatitis Study 2 (NAPS2)

DC Whitcomb, D Yadav, S Adam, RH Hawes… - Pancreatology, 2008 - Elsevier
Background: Recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) are complex
syndromes associated with numerous etiologies, clinical variables and complications. We …

Functional variants in the sucrase–isomaltase gene associate with increased risk of irritable bowel syndrome

M Henström, L Diekmann, F Bonfiglio, F Hadizadeh… - Gut, 2018 - gut.bmj.com
Objective IBS is a common gut disorder of uncertain pathogenesis. Among other factors,
genetics and certain foods are proposed to contribute. Congenital sucrase–isomaltase …

Combined bicarbonate conductance-impairing variants in CFTR and SPINK1 variants are associated with chronic pancreatitis in patients without cystic fibrosis

A Schneider, J Larusch, X Sun, A Aloe, J Lamb… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Idiopathic chronic pancreatitis (ICP) is a complex inflammatory
disorder associated with multiple genetic and environmental factors. In individuals without …

Histoplasmosis complicating tumor necrosis factor–α blocker therapy: a retrospective analysis of 98 cases

P Vergidis, RK Avery, LJ Wheat… - Clinical Infectious …, 2015 - academic.oup.com
Background. Histoplasmosis may complicate tumor necrosis factor (TNF)–α blocker therapy.
Published case series provide limited guidance on disease management. We sought to …

Physical and mental quality of life in chronic pancreatitis: a case-control study from the North American Pancreatitis Study 2 cohort

ST Amann, D Yadav, MM Barmada, M O'Connell… - Pancreas, 2013 - journals.lww.com
Objectives The objective of this study was to define the quality of life (QOL) in patients with
chronic pancreatitis (CP). Methods We studied 443 well-phenotyped CP subjects and 611 …

[HTML][HTML] Genetic risk score in diabetes associated with chronic pancreatitis versus type 2 diabetes mellitus

MO Goodarzi, T Nagpal, P Greer, J Cui… - Clinical and …, 2019 - journals.lww.com
Methods: We used 60 T2DM single nucleotide polymorphisms to construct a weighted GRS
in 1,613 subjects from the North American Pancreatitis Study 2 and 2,685 subjects from the …

Management of postprandial diarrhea syndrome

ME Money, M Camilleri - The American journal of medicine, 2012 - Elsevier
Unexpected, urgent, sometimes painful bowel movements after eating are common
complaints among adults. Without a clear etiology, if pain is present and resolves with the …