Lifestyle risk factors for serrated colorectal polyps: a systematic review and meta-analysis
L Bailie, MB Loughrey, HG Coleman - Gastroenterology, 2017 - Elsevier
Background & Aims Certain subsets of colorectal serrated polyps (SP) have malignant
potential. We performed a systematic review and meta-analysis to investigate the …
potential. We performed a systematic review and meta-analysis to investigate the …
[HTML][HTML] QuPath: Open source software for digital pathology image analysis
P Bankhead, MB Loughrey, JA Fernández… - Scientific reports, 2017 - nature.com
QuPath is new bioimage analysis software designed to meet the growing need for a user-
friendly, extensible, open-source solution for digital pathology and whole slide image …
friendly, extensible, open-source solution for digital pathology and whole slide image …
Alcohol, smoking and the risk of premalignant and malignant colorectal neoplasms
IO Fagunwa, MB Loughrey, HG Coleman - Best practice & research …, 2017 - Elsevier
Colorectal cancer (CRC) is the third most common cancer worldwide and has a complex
aetiology consisting of environmental and genetic factors. In this review, we evaluate the …
aetiology consisting of environmental and genetic factors. In this review, we evaluate the …
[HTML][HTML] Dataset for pathology reporting of colorectal cancer: recommendations from the International Collaboration on Cancer Reporting (ICCR)
MB Loughrey, F Webster, MJ Arends, I Brown… - Annals of …, 2022 - journals.lww.com
Objective: The aim of this study to describe a new international dataset for pathology
reporting of colorectal cancer surgical specimens, produced under the auspices of the …
reporting of colorectal cancer surgical specimens, produced under the auspices of the …
[HTML][HTML] Swarm learning for decentralized artificial intelligence in cancer histopathology
Artificial intelligence (AI) can predict the presence of molecular alterations directly from
routine histopathology slides. However, training robust AI systems requires large datasets …
routine histopathology slides. However, training robust AI systems requires large datasets …
[PDF][PDF] Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia
EG Vazquez, N Nasreddin, GN Valbuena… - Cell Stem Cell, 2022 - cell.com
Intestinal homeostasis is underpinned by LGR5+ve crypt-base columnar stem cells (CBCs),
but following injury, dedifferentiation results in the emergence of LGR5− ve regenerative …
but following injury, dedifferentiation results in the emergence of LGR5− ve regenerative …
[PDF][PDF] Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study
Deep learning (DL) can accelerate the prediction of prognostic biomarkers from routine
pathology slides in colorectal cancer (CRC). However, current approaches rely on …
pathology slides in colorectal cancer (CRC). However, current approaches rely on …
Challenging the cancer molecular stratification dogma: intratumoral heterogeneity undermines consensus molecular subtypes and potential diagnostic value in …
Purpose: A number of independent gene expression profiling studies have identified
transcriptional subtypes in colorectal cancer with potential diagnostic utility, culminating in …
transcriptional subtypes in colorectal cancer with potential diagnostic utility, culminating in …
British Society of Gastroenterology/Association of Coloproctologists of Great Britain and Ireland guidelines for the management of large non-pedunculated colorectal …
These guidelines provide an evidence-based framework for the management of patients
with large non-pedunculated colorectal polyps (LNPCPs), in addition to identifying key …
with large non-pedunculated colorectal polyps (LNPCPs), in addition to identifying key …
[HTML][HTML] BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1tumour phenotype
Introduction Individuals with germline mutations in the BRCA1 gene have an elevated risk of
developing breast cancer, and often display characteristic clinicopathological features. We …
developing breast cancer, and often display characteristic clinicopathological features. We …