User profiles for "author:Sarah Watson"

Sarah Watson

Institut Curie
Verified email at curie.fr
Cited by 2560

[HTML][HTML] The management of desmoid tumours: a joint global consensus-based guideline approach for adult and paediatric patients

B Alman, S Attia, C Baumgarten, C Benson… - European Journal of …, 2020 - Elsevier
Desmoid tumor (DT; other synonymously used terms: Desmoid-type fibromatosis,
aggressive fibromatosis) is a rare and locally aggressive monoclonal, fibroblastic …

Pragmatic issues in biomarker evaluation for targeted therapies in cancer

A De Gramont, S Watson, LM Ellis, J Rodón… - Nature reviews Clinical …, 2015 - nature.com
Predictive biomarkers are becoming increasingly important tools in drug development and
clinical research. The importance of using both guidelines for specimen acquisition and …

Influence of geriatric consultation with comprehensive geriatric assessment on final therapeutic decision in elderly cancer patients

P Chaïbi, N Magné, S Breton, A Chebib… - Critical reviews in …, 2011 - Elsevier
Elderly patients represent a heterogeneous population in which decisions on cancer
treatment are often difficult. The present study aims to report a 2-year period of the activity of …

Lipoprotein-associated phospholipase A (2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies.

A Thompson, P Gao, L Orfei, S Watson… - Lancet (London …, 2010 - europepmc.org
Background Lipoprotein-associated phospholipase A (2)(Lp-PLA (2)), an inflammatory
enzyme expressed in atherosclerotic plaques, is a therapeutic target being assessed in trials …

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

P Zanoni, SA Khetarpal, DB Larach… - Science, 2016 - science.org
Scavenger receptor BI (SR-BI) is the major receptor for high-density lipoprotein (HDL)
cholesterol (HDL-C). In humans, high amounts of HDL-C in plasma are associated with a …

Melt generation by plumes: a study of Hawaiian volcanism

S WATSON, DAN McKenzie - Journal of Petrology, 1991 - academic.oup.com
The mantle plume underlying the Hawaiian Swell has been modelled numerically using a
stationary steady axisymmetric plume under a solid conducting lid. A method of calculating …

Children's arithmetic development: It is number knowledge, not the approximate number sense, that counts

SM Göbel, SE Watson, A Lervåg… - Psychological …, 2014 - journals.sagepub.com
In this article, we present the results of an 11-month longitudinal study (beginning when
children were 6 years old) focusing on measures of the approximate number sense (ANS) …

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

J Holst, S Watson, MS Lord, SS Eamegdool… - Nature …, 2010 - nature.com
Surprisingly little is known about the effects of the physical microenvironment on
hemopoietic stem and progenitor cells. To explore the physical effects of matrix elasticity on …

SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas

F Le Loarer, S Watson, G Pierron, VT de Montpreville… - Nature …, 2015 - nature.com
While investigating cohorts of unclassified sarcomas by RNA sequencing, we identified 19
cases with inactivation of SMARCA4, which encodes an ATPase subunit of BAF chromatin …

Transcriptomic definition of molecular subgroups of small round cell sarcomas

S Watson, V Perrin, D Guillemot… - The Journal of …, 2018 - Wiley Online Library
Sarcoma represents a highly heterogeneous group of tumours. We report here the first
unbiased and systematic search for gene fusions combined with unsupervised expression …