User profiles for "author:Steve Hughes"

Steve Hughes

Professor of International Organisations, Newcastle University
Verified email at ncl.ac.uk
Cited by 1191

High-Flavonol Tomatoes Resulting from the Heterologous Expression of the Maize Transcription Factor Genes LC and C1

A Bovy, R de Vos, M Kemper, E Schijlen… - The Plant …, 2002 - academic.oup.com
Flavonoids are a group of polyphenolic plant secondary metabolites important for plant
biology and human nutrition. In particular flavonols are potent antioxidants, and their dietary …

[HTML][HTML] Consensus guidelines for CSF and blood biobanking for CNS biomarker studies

CE Teunissen, H Tumani, JL Bennett… - Multiple sclerosis …, 2011 - hindawi.com
There is a long history of research into body fluid biomarkers in neurodegenerative and
neuroinflammatory diseases. However, only a few biomarkers in cerebrospinal fluid (CSF) …

[HTML][HTML] A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice

R De Alwis, ES Gan, S Chen, YS Leong, HC Tan… - Molecular Therapy, 2021 - cell.com
A self-transcribing and replicating RNA (STARR)-based vaccine (LUNAR-COV19) has been
developed to prevent SARS-CoV-2 infection. The vaccine encodes an alphavirus-based …

Novel polymorphisms in the caprine PrP gene: a codon 142 mutation associated with scrapie incubation period

W Goldmann, T Martin, J Foster… - Journal of General …, 1996 - microbiologyresearch.org
Age at disease onset and rate of progression of transmissible spongiform encephalopathies
in man, sheep and mice are modulated by the host genome, in particular by the PrP gene …

Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis

C Teunissen, T Menge, A Altintas… - Multiple Sclerosis …, 2013 - journals.sagepub.com
The choice of appropriate control group (s) is critical in cerebrospinal fluid (CSF) biomarker
research in multiple sclerosis (MS). There is a lack of definitions and nomenclature of …

The international labour organisation

S Hughes - New Political Economy, 2005 - Taylor & Francis
Every day we are reminded that, for everybody, work is a defining feature of human
existence. It is the means of sustaining life and of meeting basic needs. But it is also the …

Clinical development of an antisense therapy for the treatment of transthyretin-associated polyneuropathy

EJ Ackermann, S Guo, S Booten, L Alvarado… - Amyloid, 2012 - Taylor & Francis
Transthyretin (TTR)-associated amyloidosis is a late-onset autosomal-dominant genetic
disease. Over 100 amyloidogenic mutations have been identified in TTR which destabilize …

The role of nitrogen deposition in widespread plant community change across semi-natural habitats

CD Field, NB Dise, RJ Payne, AJ Britton, BA Emmett… - Ecosystems, 2014 - Springer
Experimental studies have shown that deposition of reactive nitrogen is an important driver
of plant community change, however, most of these experiments are of short duration with …

Cost-effectiveness analyses of natalizumab (Tysabri®) compared with other disease-modifying therapies for people with highly active relapsing-remitting multiple …

R Gani, G Giovannoni, D Bates, B Kemball… - …, 2008 - Springer
Abstract Background Natalizumab (Tysabri®) is a new disease-modifying therapy that has
been shown to be clinically effective in patients with relapsing-remitting multiple sclerosis …

Guidelines for uniform reporting of body fluid biomarker studies in neurologic disorders

S Gnanapavan, H Hegen, M Khalil, B Hemmer… - Neurology, 2014 - AAN Enterprises
Objective: The aim of these guidelines is to make the process of reporting body fluid
biomarker studies in neurologic disorders more uniform and transparent, in line with existing …