Article Text

other Versions

Download PDFPDF
Review
Imaging in inflammatory bowel disease: current and future perspectives
  1. Nader Shaban1,
  2. Caroline L Hoad1,2,
  3. Iyad Naim1,2,
  4. Meshari Alshammari1,2,
  5. Shellie Jean Radford1,2,
  6. Christopher Clarke3,
  7. Luca Marciani1,2,
  8. Gordon Moran1,2
  1. 1NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK
  2. 2NIHR Nottingham Biomedical Research Centre, University of Nottingham University Park Campus, Nottingham, UK
  3. 3Department of Radiology, Nottingham University Hospitals NHS Trust, Nottingham, UK
  1. Correspondence to Professor Gordon Moran, NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham NG7 2UH, UK; Gordon.Moran{at}nottingham.ac.uk

Abstract

The use of cross-sectional imaging and ultrasonography has long complemented endoscopic assessment of inflammatory bowel disease (IBD). Clinical symptoms alone are often not enough to assess disease activity, so a reliance on non-invasive techniques is essential. In this paper, we aim to examine the current use of radiological modalities in aiding the management of patients with IBD. We focus on the various sections of the gastrointestinal tract and how different modalities can aid in assessing current disease state and response to treatments. We also have a look at how newer sequences in cross-sectional imaging and ultrasonography can allow for better differentiation of disease activity (ie, fibrotic vs inflammatory) as well improve evaluation of small bowel, colonic and perianal disease. Furthermore, we examine how advanced image processing has the potential to allow radiology to be a surrogate for biomarkers. An example of this is explored when reviewing the ability of MR sequences to quantify visceral fat, which potentially plays a role in determining disease activity in Crohn’s disease. Lastly, we look into the expected role for artificial intelligence to be used as an adjunct to radiology to better improve IBD evaluation.

  • magnetic resonance imaging
  • ultrasonography
  • inflammatory bowel disease
  • computer tomography
  • imaging

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes

  • Twitter @Shellie_Jean

  • Contributors GM is acting as the submission’s guarantor. NS, CLH, IN, MA, SJR, CC and LM have all contributed to the writing of this manuscript. GM is senior and corresponding author.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests GM receives funding from AztraZenca and Jansen and is a consultant for Alimentiv.

  • Provenance and peer review Commissioned; internally peer reviewed.

Linked Articles

  • UpFront
    R Mark Beattie