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Use of intravenous hyoscine butylbromide (Buscopan) during gastrointestinal endoscopy
  1. Thomas Lee1,2,
  2. John Anderson3,4,
  3. Siwan Thomas-Gibson5,6,7,
  4. Colin Rees2,8,9,10
  5. On behalf of the British Society of Gastroenterology, Joint Advisory Group on Gastrointestinal Endoscopy and Bowel Cancer Screening Programme
  1. 1 Gastroenterology, Northumbria Healthcare NHS Foundation Trust, UK
  2. 2 Northern Region Endoscopy Group (NREG), Newcastle, UK
  3. 3 Department of Gastroenterology, Cheltenham General Hospital, Cheltenham, UK
  4. 4 Bowel Cancer Screening Programme Accreditation Panel, London, UK
  5. 5 Wolfson Unit for Endoscopy, St Mark’s Hospital, London, UK
  6. 6 Surgery, Imperial College, London, UK
  7. 7 Joint Advisory Group (on Gastrointestinal Endoscopy), London, UK
  8. 8 Department of Gastroenterology, South Tyneside General Hospital, South Shields, UK
  9. 9 British Society of Gastroenterology, London, UK
  10. 10 Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK
  1. Correspondence to Dr Thomas Lee; tom.lee{at}

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The Medicines and Healthcare products Regulatory Agency has recently circulated a Drug Safety Update regarding the risk of serious adverse events following the use of intravenous hyoscine butylbromide (Buscopan) in patients with underlying cardiac disease.1

Buscopan is commonly used during endoscopic procedures. It induces smooth muscle relaxation and reduces spasm in the gastrointestinal tract. It is used during upper gastrointestinal endoscopy and small bowel enteroscopy to reduce contraction and aid mucosal visualisation.2 During endoscopic retrograde cholangiopancreatography, it is used to facilitate access to the common bile duct during cannulation of the ampulla of Vater.3 During colonoscopy, it is …

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  • Contributors CR conceived the idea for the article. TJWL wrote the original draft. All authors contributed to the intellectual content and editing of the document.

  • Competing interests None declared

  • Provenance and peer review Not commissioned; internally peer reviewed.

  • Data sharing statement No source data to share.

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